Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
產(chǎn)品名稱： Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
英文名稱： Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
產(chǎn)品編號： DMC100420
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： China
品牌商標(biāo)： DIMA Biotech
更新時(shí)間： null
使用范圍：
締碼生物科技（武漢）有限公司
- 聯(lián)系人 :
- 地址 : 武漢市洪山區(qū)東湖高新區(qū)高新大道666號光谷生物城B7
- 郵編 : 430070
- 所在區(qū)域 : 湖北
- 電話 : 151****5168 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : cygao@dimabio.com
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.