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Human Growth Factors & Cytokines
Recombinant Human Activin A


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Synonyms :
None
Description :
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Catalog #:
120-14E
Source :
E.coli
Purity :
Greater than 97% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS 
PubMed Link :
Activin+AND+A+AND+human
Country of Origin :
USA
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Size A
2μg
$80?
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Size B
10μg
$195?
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Size C
1mg
$5200?
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Special Sizes: 
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures. 

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