Active EGF全長蛋白質
產品名稱: Active EGF全長蛋白質
英文名稱: Beta urogastrone EGF EGF_HUMAN Epidermal growth factor HOMG4 OTTHUMP00000219721 OTTHUMP00000219722 Pro epidermal growth factor URG Urogastro
產品編號: ab9863
產品價格: 0
產品產地: 英國
品牌商標: abcam
更新時間: null
使用范圍: null
- 聯系人 :
- 地址 : 深圳市寶安區西鄉寶民二路賢基大廈4E
- 郵編 :
- 所在區域 : 廣東
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- 性質Recombinant
- 來源E. coli
技術指標
Our?Abpromise guarantee?covers the use of?ab9863?in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 應用
Functional Studies
SDS-PAGE
- 內毒素水平< 0.100?Eu/μg
- 形式Lyophilised
- 補充說明Murine EGF is fully biologically active when compared with standards. The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.
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濃度由溶解方法決定?
制備和貯存
- 穩定性和存儲
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product has been formulized from 10mM Sodium phosphate. pH 8.0.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 復溶ADD 500UL WATER
常規信息
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別名
- Beta urogastrone
- EGF
- EGF_HUMAN
see all - 功能EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
- 組織特異性Expressed in kidney, salivary gland, cerebrum and prostate.
- 疾病相關Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.
- 序列相似性Contains 9 EGF-like domains.
Contains 9 LDL-receptor class B repeats. - 細胞定位Membrane.
