Rac信號(hào)傳導(dǎo)分子激活檢測(cè)試劑盒-試劑盒-抗體-生物在線

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武漢紐斯特生物技術(shù)有限公司
Rac信號(hào)傳導(dǎo)分子激活檢測(cè)試劑盒

Rac信號(hào)傳導(dǎo)分子激活檢測(cè)試劑盒

商家詢價(jià)

產(chǎn)品名稱: Rac信號(hào)傳導(dǎo)分子激活檢測(cè)試劑盒

英文名稱: Rac Activation Assay Kit

產(chǎn)品編號(hào): 80501

產(chǎn)品價(jià)格: null

產(chǎn)品產(chǎn)地: 美國

品牌商標(biāo): NewEastBio

更新時(shí)間: null

使用范圍: IPWB

武漢紐斯特生物技術(shù)有限公司
  • 聯(lián)系人 :
  • 地址 : 武漢市東湖新技術(shù)開發(fā)區(qū)光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區(qū)域 : 湖北
  • 電話 : 186****7297 點(diǎn)擊查看
  • 傳真 : 點(diǎn)擊查看
  • 郵箱 : neweast3@126.com

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Rac Activation Assay Kit [80501]
[20 assays]
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Product Highlight

  • Configuration-specific monoclonal anti-Rac-GTP antibody based
  • This monoclonal antibody specifically recognizes Rac-GTP, but not Rac-GDP
  • Providing shorter experimental time
  • Providing reliable results with consistent reproducibility than other Rac activation assay kits
  • Could be used to monitor the activation of Rac in cells and in tissues by immunohistochemistry

Product Description

    Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive.

    Currently the activation of Rac proteins is assayed with the binding of GTP-bound Rac to the p21-binding domain (PBD) of p21-activated protein kinase (PAK). This method is based on the observation that the active, GTP-bound Rac could bind to the PBD of PAK. However, the reproducibility of this method is poor. This is partially due to the relatively quick hydrolysis of GTP to GDP during the assay procedure, and the low binding affinity of PBD to Rac-GTP.

    These anti-Rac-GTP monoclonal antibody can also be used to monitor the activation of Rac in cells and in tissues by immunohistochemistry.

    NewEast Biosciences Rac Activation Assay Kit provides a simple and fast method to monitor the activation of Rac. Each kit provides sufficient quantities to perform 20 assays.

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Assay Principle