PRKAB1 monoclonal antibody (M02), clone 2C3
產品名稱: PRKAB1 monoclonal antibody (M02), clone 2C3
英文名稱: PRKAB1 monoclonal antibody (M02), clone 2C3
產品編號: H00005564-M02
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant PRKAB1.
- Immunogen:
- PRKAB1 (AAH01007, 1 a.a. ~ 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEFLAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSSSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.

Western Blot detection against Immunogen (55.44 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)

- PRKAB1 monoclonal antibody (M02), clone 2C3 Western Blot analysis of PRKAB1 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence

enlarge this image- Immunofluorescence of monoclonal antibody to PRKAB1 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)

- Detection limit for recombinant GST tagged PRKAB1 is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5564
- GeneBank Accession#:
- BC001007
- Protein Accession#:
- AAH01007
- Gene Name:
- PRKAB1
- Gene Alias:
- AMPK,HAMPKb,MGC17785
- Gene Description:
- protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Omim ID:
- 602740
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq
- Other Designations:
- 5'-AMP-activated protein kinase beta-1 subunit,AMP-activated protein kinase beta 1 non-catalytic subunit,AMP-activated protein kinase beta subunit,AMPK beta -1 chain,AMPK beta 1,protein kinase, AMP-activated, noncatalytic, beta-1

