?


Human Growth Factors & Cytokines
Recombinant Human LIGHT





?





		Synonyms :
TNFSF14, HVEM-L



		Description :
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3.  It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes.  LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.  Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues.  Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.


*Human LIGHT(Catalog Number 310-09B) has replaced Human LIGHT(Catalog Number 310-09)




		Catalog #:
310-09B



		Source :
Hi-5 Insect cells



		Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Testing in progress.



                AA Sequence :
RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV 



		PubMed Link :
LIGHT+AND+TNFSF14


Country of Origin :
USA
















        Size A
3μg
$80?
?


?



        Size B
15μg
$195?
?


?















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.