Anti-AKR1C3抗體
產(chǎn)品名稱(chēng)： Anti-AKR1C3抗體
英文名稱(chēng)： 17 beta HSD 5 antibody 17 beta hydroxysteroid dehydrogenase type 5 antibody 17-beta-HSD 5 antibody 17-beta-hydroxysteroid dehydrogenase type 5 antibod
產(chǎn)品編號(hào)： ab196673
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 英國(guó)
品牌商標(biāo)： abcam
更新時(shí)間： null
使用范圍：
- 聯(lián)系人 :
- 地址 : 深圳市寶安區(qū)西鄉(xiāng)寶民二路賢基大廈4E
- 郵編 :
- 所在區(qū)域 : 廣東
- 電話(huà) : 133****4454 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : 1484332550@qq.com
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- 經(jīng)測(cè)試應(yīng)用IHC-P,?WBmore details
- 種屬反應(yīng)性
與反應(yīng):?Rat, Human
- 免疫原
Recombinant full length protein corresponding to Human AKR1C3.
Database link:?P42330 - 陽(yáng)性對(duì)照
- K562, Jurkat, HepG2, A549 and SW620 cell extracts; Human esophageal cancer, rat kidney and rat brain tissues.
性能
- 形式Liquid
- 存放說(shuō)明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
- 存儲(chǔ)溶液pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride
PBS without Mg2+?and Ca2+. -
濃度100 μl 濃度為 1 mg/ml?
- 純度Immunogen affinity purified
- 克隆多克隆
- 同種型IgG
- 研究領(lǐng)域
應(yīng)用
Our?Abpromise guarantee?covers the use of?ab196673?in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
靶標(biāo)
- 功能Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
- 組織特異性Expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. The dominant HSD in prostate and mammary gland. In the prostate, higher levels in epithelial cells than in stromal cells. In the brain, expressed in medulla, spinal cord, frontotemporal lobes, thalamus, subthalamic nuclei and amygdala. Weaker expression in the hippocampus, substantia nigra and caudate.
- 序列相似性Belongs to the aldo/keto reductase family.
- 細(xì)胞定位Cytoplasm.
- Information by UniProt
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數(shù)據(jù)庫(kù)鏈接
- Entrez Gene: 8644?Human
- Entrez Gene: 307092?Rat
- Omim: 603966?Human
- SwissProt: P42330?Human
- Unigene: 78183?Human
- Unigene: 10030?Rat
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別名
- 17 beta HSD 5 antibody
- 17 beta hydroxysteroid dehydrogenase type 5 antibody
- 17-beta-HSD 5 antibody
see all
Anti-AKR1C3 antibody 圖像
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Western blot - Anti-AKR1C3 antibody (ab196673)All lanes :?Anti-AKR1C3 antibody (ab196673) at 1/500 dilution
Lane 1 :?K562 cell extract
Lane 2 :?Jurkat cell extract
Lane 3 :?HepG2 cell extract
Lane 4 :?A549 cell extract
Lane 5 :?SW620 cell extract
Predicted band size :?37 kDa
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AKR1C3 antibody (ab196673)Immunohistochemical analysis of paraffin-embedded Human esophageal cancer?tissue labeling AKR1C3 with ab196673 at 1/100 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AKR1C3 antibody (ab196673)Immunohistochemical analysis of paraffin-embedded rat kidney tissue labeling AKR1C3 with ab196673 at 1/100 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AKR1C3 antibody (ab196673)Immunohistochemical analysis of paraffin-embedded rat brain tissue labeling AKR1C3?with ab196673 at 1/100 dilution.