MMP16 Pre-design Chimera RNAi
產(chǎn)品名稱： MMP16 Pre-design Chimera RNAi
英文名稱： MMP16 Pre-design Chimera RNAi
產(chǎn)品編號： H00004325-R01
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
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- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens matrix metallopeptidase 16 (membrane-inserted) (MMP16), transcript variant 1, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_005941
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4325
- Gene Name:
- MMP16
- Gene Alias:
- C8orf57,MMP-X2,MT-MMP2,MT-MMP3,MT3-MMP
- Gene Description:
- matrix metallopeptidase 16 (membrane-inserted)
- Omim ID:
- 602262
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq
- Other Designations:
- matrix metalloproteinase 16,matrix metalloproteinase 16 (membrane-inserted),membrane-type matrix metalloproteinase 3,membrane-type-3 matrix metalloproteinase
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bronchopulmonary Dysplasia
- Cardiovascular Diseases
- Celiac Disease
- Chorioamnionitis
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Liver Cirrhosis
- Metabolic Syndrome X
- Neoplasms
- Obstetric Labor, Premature
- Osteoporosis
- Pre-Eclampsia