Size??100ug
Cat code??200753
Species Cross-reactivity??H,M,R
Key Application??WB,IP
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG2b
Molecular Weight??69kDa
Sensitivity??This antibody detects endogenous levels of SWAP70 and does not cross-react with related proteins.
Immunogen??Purified recombinant human SWAP70 protein fragments expressed in E.coli.
UniProt Number??Q9UH65
GeneBank ID??NM_015055.2
Subcellular location??Cytoplasm. Cell membrane. Nucleus. Cell projection ? lamellipodium.
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Altername??Switch-associated protein 70
Gene_symbol??HSPC321; SWAP-70; FLJ39540; KIAA0640
Summary??null
UniPort summary  Function??Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which,
independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane
ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated
phosphatidylinositol (3,4)-bisphosphate production and cell protrusion
Application Images :??
Western blot detection of SWAP70 in Rat liver，Daudi，3T3，Raw264.7，Hela&PC12 cell lysates and  using SWAP70 antibody (1:1000 diluted). 
Predicted band size: 70KDa 
Observed band size: 70KDa
Immunoprecipitation analysis of Hela cell lysate using SWAP70 antibody.