Recombinant Human IL-4R alpha Protein,mFc Tag
產品名稱： Recombinant Human IL-4R alpha Protein,mFc Tag
英文名稱： Recombinant Human IL-4R alpha Protein,mFc Tag
產品編號： 94074ES
產品價格： 詢價
產品產地： Yeasen
品牌商標： Yeasen
更新時間： 2026-02-11T13:28:21
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
產品介紹
Interleukin4 (IL4) is a cytokine with several important functions in the immune system. It primarily helps activate B cells and produce antibodies, especially IgE antibodies related to allergies. It also promotes the differentiation of T helper cells into Th2 cells, supporting humoral immune responses. Additionally, IL4 can help suppress inflammation in certain situations, maintaining immune balance. It is mainly secreted by activated T cells, mast cells, and basophils, and serves as a key target for interventions in various diseases, including allergies and asthma. Due to its crucial role in immune regulation, IL4 has been a significant focus in immunology research.
The IL4RA protein, also known as the interleukin-4 receptor alpha chain, is an important cell surface receptor primarily involved in regulating the immune system. When it binds with interleukin-4 (IL-4), it triggers signaling pathways that promote T cell differentiation and B cell proliferation. IL4RA plays a significant role in allergic reactions and asthma, and its gene polymorphisms are associated with susceptibility to various immune-related diseases.
產品性質
|
產品別稱
|
IL4R,CD124,IL4RA
|
|
種屬
|
Human
|
|
表達序列
|
Met 26 - His 232
|
|
Accession
|
P24394-1
|
|
標簽
|
C-mFc Tag
|
|
表達系統
|
HEK293
|
|
分子量
|
The protein has a predicted MW of 48.4 kDa
|
|
純度
|
> 90% as determined by SDS-PAGE
|
|
內毒素
|
< 1.0 EU per μg by the LAL method.
|
|
制劑
|
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
|
|
外觀
|
Liquid
|
|
生物活性
|
ELISA: Human IL-4R alpha Protein; mFc Tag was immobilized at 5 μg/ml (100 μL/well). Increasing concentrations of Anti-IL-4R hIgG1 Antibody were added.
|
產品特色
高純度、高活性、低內毒素、高批間一致性
應用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Bioactivity-ELISA
Figure 2.Human IL-4R alpha Protein; mFc Tag was immobilized at 5 μg/ml (100 μL/well). Increasing concentrations of Anti-IL-4R hIgG1 Antibody were added.
存儲條件
-85 ~ -65℃保存，收到貨之日起，6個月有效期。避免反復凍融，建議等分分裝為一次實驗使用量，分裝后，-80℃凍存。