TNF-β, Human
產品名稱： TNF-β, Human
英文名稱：
產品編號： CB055-2563
產品價格： 0
產品產地： 美國
品牌商標： ExCell Bio
更新時間： null
使用范圍： null
上海吉泰依科賽生物科技有限公司
- 聯系人 :
- 地址 : 上海市徐匯區(qū)桂平路481號18號樓5層
- 郵編 : 200233
- 所在區(qū)域 : 上海
- 電話 : 021-6439-8855 點擊查看
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- 郵箱 : marketing@excellbio.com
TNF is secreted by macrophages, monocytes, neutrophils, T-cells, NK-cells following their stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-alpha while CD8 cells secrete little or no TNF-alpha. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL2, GM-CSF. TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses.
Recombinant Human TNF-β produced in E. coli is is a glycosylated polypeptide chain of 172 amino acids. A fully biologically active molecule,rhTNF-β has a molecular mass of 18.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at ExCell Bio.