POLG2 MaxPab rabbit polyclonal antibody (D01)
產品名稱： POLG2 MaxPab rabbit polyclonal antibody (D01)
英文名稱： POLG2 MaxPab rabbit polyclonal antibody (D01)
產品編號： H00011232-D01
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human POLG2 protein.
- Immunogen:
- POLG2 (AAH09194.1, 1 a.a. ~ 485 a.a) full-length human protein.
- Sequence:
- MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPAYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of POLG2 expression in transfected 293T cell line (H00011232-T02) by POLG2 MaxPab polyclonal antibody.
Lane 1: POLG2 transfected lysate(54.90 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of POLG2 transfected lysate using anti-POLG2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with POLG2 purified MaxPab mouse polyclonal antibody (B01P) (H00011232-B01P).
- Protocol Download
- Entrez GeneID:
- 11232
- GeneBank Accession#:
- BC009194
- Protein Accession#:
- AAH09194.1
- Gene Name:
- POLG2
- Gene Alias:
- HP55,MTPOLB,PEOA4,POLB,POLG-BETA,POLGB
- Gene Description:
- polymerase (DNA directed), gamma 2, accessory subunit
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions
- Other Designations:
- mitochondrial DNA polymerase, accessory subunit
- Gene Pathway
- Related Disease
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hepatitis C, Chronic
- Liver Cirrhosis
- Lung carcinoma, small cell
- Lung Neoplasms
- Ophthalmoplegia, Chronic Progressive External