SENP2 polyclonal antibody
產品名稱： SENP2 polyclonal antibody
英文名稱： SENP2 polyclonal antibody
產品編號： PAB2415
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SENP2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SENP2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.
Zhang H, Saitoh H, Matunis MJ.Mol Cell Biol. 2002 Sep;22(18):6498-508.
- 2.
- Association of the human SUMO-1 protease SENP2 with the nuclear pore.
Hang J, Dasso M.J Biol Chem. 2002 May 31;277(22):19961-6. Epub 2002 Mar 14.
- 3.
- Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation.
Nishida T, Kaneko F, Kitagawa M, Yasuda H.J Biol Chem. 2001 Oct 19;276(42):39060-6. Epub 2001 Aug 6.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of SENP2 polyclonal antibody (Cat # PAB2415) in HL-60 cell lysate. SENP2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SENP2 polyclonal antibody (Cat # PAB2415) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 59343
- Protein Accession#:
- NP_067640;Q9HC62
- Gene Name:
- SENP2
- Gene Alias:
- AXAM2,DKFZp762A2316,KIAA1331,SMT3IP2
- Gene Description:
- SUMO1/sentrin/SMT3 specific peptidase 2
- Omim ID:
- 608261
- Gene Ontology:
- Hyperlink
- Gene Summary:
- SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM
- Other Designations:
- SUMO1/sentrin/SMT3 specific protease 2,sentrin-specific protease
- Gene Pathway