Anti-ErbB2 (V777A) mouse monoclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-ErbB2 (V777A) mouse monoclonal Antibody

Anti-ErbB2 (V777A) mouse monoclonal Antibody

商家詢價

產品名稱： Anti-ErbB2 (V777A) mouse monoclonal Antibody

英文名稱： Anti-ErbB2 (V777A) mouse monoclonal Antibody

產品編號： 26080

產品價格： null

產品產地： 美國

品牌商標： NewEastBio

更新時間： null

使用范圍： ELISA、WB、 IF、IHC

武漢紐斯特生物技術有限公司
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ERBB2 (V777A) [26080]
[100 μL]		 ?

Catalog Number:??26080
Gene Symbol:??ERBB2/HER2/Neu
Description: ??Anti-ErbB2 (V777A) mouse monoclonal Antibody
Background: ??The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22). HER2 proteins have been shown to form clusters in cell membranes that may play a role in tumorigenesis. Mutations of ErbB2 protein, including V777A, have been indicated in human cancers.
Immunogen: ??A synthetic peptide surround the 777A codon of ErbB2 protein.
Tested Applications: ??ELISA, WB, IF, IHC
Recommended Dilutions: ??
ELISA: 1:500-1:5000?
WB: 1:200-1:2000?
IF: 1:100?
IHC: 1:50-1:100
Concentration: ??0.2 mg/ml
Host: ??mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+?and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Recognizes V777A mutant but not wild type ErbB2 protein, of vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence:??
Immunofluorescence of cells expressing ErbB2 proteins with anti-ErbB2 (V777A) antibody. HEK293T cells were transfected with pCDNA3-GFP- ErbB2 WT plasmid (left column) or pCDNA3-GFP-ErbB2 (V777A) plasmid (right column), then fixed and stained with anti-ErbB2 (V777A) monoclonal antibody (Cat. #26080).