CDKN1A (phospho T57) Peptide-蛋白質(zhì)/抗原/多肽-試劑-生物在線

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亞諾法生技股份有限公司(Abnova)
CDKN1A (phospho T57) Peptide

CDKN1A (phospho T57) Peptide

商家詢價(jià)

產(chǎn)品名稱: CDKN1A (phospho T57) Peptide

英文名稱: CDKN1A (phospho T57) Peptide

產(chǎn)品編號(hào): P1372

產(chǎn)品價(jià)格: 0

產(chǎn)品產(chǎn)地: 臺(tái)灣

品牌商標(biāo): Abnova

更新時(shí)間: null

使用范圍: null

亞諾法生技股份有限公司(Abnova)
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDKN1A.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T57 of human CDKN1A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • ELISA (1:1000)
    Dot Blot (1:500)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CDKN1A (phospho T57) polyclonal antibody (Cat # PAB0556). Western blot analysis of CDKN1A expression in human colon.
  • Protocol Download
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with CDKN1A (phospho T57) polyclonal antibody (Cat # PAB0556) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • ELISA
  • Dot Blot (Peptide)
  • Dot Blot (Peptide)
  • Dot blot analysis of CDKN1A (phospho T57) polyclonal antibody (Cat # PAB0556) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 ug/mL.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1026
  • Protein Accession#:
  • NP_000380;P38936
  • Gene Name:
  • CDKN1A
  • Gene Alias:
  • CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1
  • Gene Description:
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • Gene Summary:
  • This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. [provided by RefSeq
  • Other Designations:
  • CDK-interaction protein 1,DNA synthesis inhibitor,OTTHUMP00000016298,cyclin-dependent kinase inhibitor 1A,melanoma differentiation associated protein 6,wild-type p53-activated fragment 1
  • Interactome