Anti-Sti1p (HOP) pAb
產(chǎn)品名稱： Anti-Sti1p (HOP) pAb
英文名稱： Sti1p (HOP) Polyclonal Antibody
產(chǎn)品編號(hào)： SPC-203D
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 加拿大
品牌商標(biāo)： StressMarq
更新時(shí)間： null
使用范圍： WB, not yet tested in other applications
StressMarq
- 聯(lián)系人 :
- 地址 : 加拿大
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- 郵箱 : hedyl@stressmarq.com
The stress inducible protein Sti1p is also commonly known as Hsp70-Hsp90 organization protein (HOP). It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones Hsp70 and Hsp90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. Hsp70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the Hsp70/Hsp90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).