PeproTech重組人sCD27 Ligand 50ug
產品名稱： PeproTech重組人sCD27 Ligand 50ug
英文名稱： Recombinant Human sCD27 Ligand
產品編號： 310-30
產品價格： 0
產品產地： 美國
品牌商標： PeproTech
更新時間： null
使用范圍： null
美國PeproTech(派普泰克)公司中國代表處
- 聯系人 :
- 地址 :  江蘇省蘇州市工業園區星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區域 : 江蘇
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- 郵箱 : peprotech.infochina@thermofisher.com
Recombinant Human sCD27 Ligand
Catalog Number:
310-30
Synonyms:
TNFSF7, CD70
Description:
CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. PeproTech’s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
AA Sequence:
HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
Source:
CHO cells
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.
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Research Interests:
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Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.
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