Size??100ul
Cat code??220015
Species Cross-reactivity??H
Key Application??WB
Host??Mouse
Clone Number??7A7-H3-D5
Antibody type??Monoclonal antibody
Purified method??
Isotype??IgG1
Molecular Weight??102kDa
Sensitivity??The antibody detects endogenous level of total HK1 protein.
Immunogen??Purified recombinant fragment of human HK1 expressed in E. Coli.
UniProt Number??P19367
GeneBank ID??NM_000188.2
Subcellular location??Mitochondrion outer membrane. Note: Its hydrophobic N-terminal sequence may be involved in membrane binding
Formulation??Ascitic fluid containing 0.03% sodium azide.
Altername??BB404130 ; Brain form hexokinase ; dea ; EC 2.7.1.1 ; Glycolytic enzyme ; HEXOKIN ; Hexokinase PI ; Hexokinase type I ; Hexokinase, tumor isozyme ; Hexokinase-1 ; Hexokinase-A ; HK I ; HK1 ; HK1 tb ; Hk1-s ; HK1-ta ; HK1-tb ; HK1-tc ; HKI ; HXK1 ; HXK1_HUMAN ; mHk1-s ;
Gene_symbol??HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc
Summary??Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009]
UniPort summary  Function??null
Application Images :??
Western blot detection of HK1 antibody in Jurkat, HepG2 and Hela cell lysates using HK1 antibody(dilution 1:500).Predicted band size:102KDa.Observed band size:102KDa.