小鼠 分化群134 配體 蛋白, Fc 標簽
產(chǎn)品名稱: 小鼠 分化群134 配體 蛋白, Fc 標簽
英文名稱: Mouse OX40 Ligand Protein, Fc Tag
產(chǎn)品編號: OXL-M5263
產(chǎn)品價格: 3045
產(chǎn)品產(chǎn)地: 中國
品牌商標: 北京百普賽斯生物科技股份有限公司
更新時間: 2025-09-19T18:06:11
使用范圍: null
| 規(guī)格 | 價格 |
| 100ug |
- 聯(lián)系人 : 團子
- 地址 : 北京經(jīng)濟技術(shù)開發(fā)區(qū)宏達北路8號5號樓4層
- 郵編 : 100176
- 所在區(qū)域 : 北京
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Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.
