Anti-RET (C634Y) Mouse Monoclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-RET (C634Y) Mouse Monoclonal Antibody

Anti-RET (C634Y) Mouse Monoclonal Antibody

商家詢價

產品名稱： Anti-RET (C634Y) Mouse Monoclonal Antibody

英文名稱： Anti-RET (C634Y) Mouse Monoclonal Antibody

產品編號： 26146

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： ELISA, WB, IHC

武漢紐斯特生物技術有限公司
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  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
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  • 郵箱 : neweast3@126.com

RET (C634Y) [26146]
[100ul]		 ?

Catalog Number:??26146
Gene Symbol:??RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
Description: ??Anti-RET (C634Y) Mouse Monoclonal Antibody
Background: ??RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprung’s disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasias type 2A and 2B, pheochromocytoma and parathyroid hyperplasia.
Immunogen: ??A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin.
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration: ??0.5 mg/ml
Host: ??Mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Recognizes C634Y mutant, but not wild-type RET of vertebrates.
Storage Conditions:?? Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of recombinant RET (C634Y) and wildtype proteins. Purified His-tagged RET (C634Y) protein (lane1) and corresponding wild-type protein (lane2) were blotted with anti-RET (C634Y) monoclonal antibody (Cat. #26146).
Immunoprecipitation/Western blot:??

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Immunofluorescence of cells expressing RET proteins with anti-RET (C634Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-RET (WT) plasmid (left column) or pCDNA3-GFP-RET (C634Y) plasmid (right column), then fixed and stained with anti-RET (C634Y) monoclonal antibody (Cat. #26146).