血管緊張素II受體樣蛋白1抗體
產品名稱： 血管緊張素II受體樣蛋白1抗體
英文名稱： Apelin Receptor
產品編號： 2430
產品價格： null
產品產地： 上海
品牌商標： 雅吉
更新時間： null
使用范圍： WB ELISA Flow-Cyt ICC IF
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| 中文名稱 | 血管緊張素II受體樣蛋白1抗體 |
| 別????名 | APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.?? |
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| 研究領域 | 心血管??細胞生物??免疫學??G蛋白偶聯受體??G蛋白信號?? |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse,? (predicted: Human,?Rat,?Dog,?Rabbit,?) |
| 產品應用 | WB=1:500-2000?ELISA=1:500-1000?Flow-Cyt=1μg/Test? not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分?子?量 | 42kDa |
| 細胞定位 | 細胞膜? |
| 性????狀 | Liquid |
| 濃????度 | 1mg/ml |
| 免?疫?原 | KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380? |
| 亞????型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲?存?液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq Function: Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. Subcellular Location: Cell membrane. Tissue Specificity: Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P35414 Gene ID: 187 Database links: Entrez Gene: 429337?Chicken Entrez Gene: 615435?Cow Entrez Gene: 187?Human Entrez Gene: 23796?Mouse Entrez Gene: 83518?Rat Omim: 600052?Human SwissProt: P35414?Human SwissProt: Q9WV08?Mouse SwissProt: Q9JHG3?Rat Unigene: 438311?Human Unigene: 29368?Mouse Unigene: 7965?Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ? |
| 產品圖片 |  Sample:Lane 1: Heart (Mouse) Lysate at 40 ug Lane 2: Heart (Rat) Lysate at 40 ug Lane 3: Cerebrum (Mouse) Lysate at 40 ug Lane 4: Cerebrum (Rat) Lysate at 40 ug Lane 5: Spinal cord (Mouse) Lysate at 40 ug Lane 6: Spinal cord (Rat) Lysate at 40 ug Primary: Anti-Apelin Receptor (bs-2430R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44/58 kD Observed band size: 50 kD  Sample:Stomach (Mouse) Lysate at 40 ug Primary: Anti-Apelin Receptor (bs-2430R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD  Positive control(blue): mouse SplenocytesIsotype Antibody (orenge): Rabbit IgG, Dilution: 1ug in 100 u1 X PBS containing 0.5% BSA Secondary Antibody(light blue): Goat anti-rabbit IgG-FITC,Dilution: 1:200 in 1 X PBS containing 0.5% BSA Primary Antibody catalog number (green): bs-2430R, Dilution: 1ug in 100ul 1X PBS containing 0.5% BSA |
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