CREB1 (phospho S133) polyclonal antibody
產品名稱： CREB1 (phospho S133) polyclonal antibody
英文名稱： CREB1 (phospho S133) polyclonal antibody
產品編號： PAB12617
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
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- 所在區域 : 臺灣
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CREB1.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S133 of human CREB1.
- Sequence:
- RPSYR
- Host:
- Rabbit
- Theoretical MW (kDa):
- 40
- Reactivity:
- Human, Rat
- Specificity:
- This antibody only recognizes ~40 KDa of human CREB1.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (1:50)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus.
Zhu DY, Lau L, Liu SH, Wei JS, Lu YM.Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9453-7. Epub 2004 Jun 14.
- Applications
- Immunoprecipitation
- The tissue lysate derived from ischemia rat brain was immunoprecipitated by CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673), then immuno-blotted by the CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617) at 1 : 500 (lane 1). Lane 2 : negative control.
- Dot Blot (Peptide)
- Dot Blot : 1 ug peptide was blot onto NC membrane.
A : CREB1 (pS133).
B : CREB1 (non-phosphorylated).
C : Non-related Phosphopeptide.
Followed by rabbit antibodies incubation at a 1 : 1000 dilution.
1. CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617).
2. CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673).
- Entrez GeneID:
- 1385
- Gene Name:
- CREB1
- Gene Alias:
- CREB,MGC9284
- Gene Description:
- cAMP responsive element binding protein 1
- Omim ID:
- 123810
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- active transcription factor CREB,cAMP-response element-binding protein-1,transactivator protein
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- Dominance, Cerebral