Anti-Cleaved PARP Monoclonal Antibody
產(chǎn)品名稱： Anti-Cleaved PARP Monoclonal Antibody
英文名稱： ADPRT;ADPRT1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL
產(chǎn)品編號： K000215M
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標： Solarbio
更新時間： null
使用范圍： WB IHC
北京索萊寶科技有限公司--實驗室產(chǎn)品
- 聯(lián)系人 :
- 地址 : 北京市通州區(qū)馬駒橋聯(lián)東U谷景盛南四街85A三層
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 010-563*1250 點擊查看
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- 郵箱 : 2748554845@qq.com
Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.