• 經測試應用WBmore details
• 種屬反應性
  與反應:?Rat, Human
• 免疫原

  Synthetic peptide, corresponding to residues in Human 12 Lipoxygenase (UniProt: P18054).

• 陽性對照
  • A431, Human spleen and Human fetal liver lysates.
• 常規說明

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^??technology. RabMAb^??technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

  Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

• 形式Liquid
• 存放說明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• 存儲溶液Preservative: 0.01% Sodium azide
  Constituents: 50% Glycerol, 0.05% BSA
• 純度Tissue culture supernatant
• 克隆單克隆
• 克隆編號EPR11380(B)
• 同種型IgG
• 研究領域
  • Signal Transduction
  ?
  • Metabolism
  ?
  • Lipid metabolism

  • Cardiovascular
  ?
  • Atherosclerosis
  ?
  • Lipoprotein metabolism

  • Cardiovascular
  ?
  • Lipids / Lipoproteins
  ?
  • Fatty Acids
  ?
  • Metabolism

  • Cancer
  ?
  • Cancer Metabolism
  ?
  • Cellular metabolic process

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  ?
  • Lipoprotein metabolism

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  ?
  • Fatty acids

  • Metabolism
  ?
  • Types of disease
  ?
  • Heart disease

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Redox metabolism
  • Fatty acid oxidation

應用

• 應用說明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

靶標

• 功能Oxygenase and 14,15-leukotriene A4 synthase activity.
• 通路Lipid metabolism; leukotriene D4 biosynthesis.
• 序列相似性Belongs to the lipoxygenase family.
  Contains 1 lipoxygenase domain.
  Contains 1 PLAT domain.
• 細胞定位Cytoplasm.

• Anti-12 Lipoxygenase antibody [ EPR11380(B)] 圖像

  • 

    Western blot - Anti-12 Lipoxygenase antibody [ EPR11380(B)] (ab168384)
    All lanes :?Anti-12 Lipoxygenase antibody [ EPR11380(B)] (ab168384) at 1/1000 dilution
    
    Lane 1 :?A431 lysate
    Lane 2 :?Human spleen lysate
    Lane 3 :?Human fetal liver lysate
    
    Lysates/proteins at 10 μg per lane.
    
    Secondary
    Goat anti-rabbit HRP at 1/2000 dilution
    
    Predicted band size :?76 kDa