• 經測試應用IHC-Pmore details
• 種屬反應性
  與反應:?Human
• 免疫原

  Fusion protein corresponding to Human APOA4 (internal sequence). (BC113596).
  Database link:?P06727

• 陽性對照
  • Human ovarian cancer and cervical cancer tissues.

性能

• 形式Liquid
• 存放說明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
• 存儲溶液pH: 7.3
  Preservative: 0.05% Sodium azide
  Constituents: 50% Glycerol, 49% PBS
• ?
• 純度Immunogen affinity purified
• 克隆多克隆
• 同種型IgG
• 研究領域
  • Signal Transduction
  ?
  • Metabolism
  ?
  • Lipid metabolism

  • Cardiovascular
  ?
  • Atherosclerosis
  ?
  • Lipoprotein metabolism

  • Cardiovascular
  ?
  • Atherosclerosis
  ?
  • Lipid transport

  • Cardiovascular
  ?
  • Lipids / Lipoproteins
  ?
  • Lipoproteins/Apolipoproteins
  • Apolipoproteins

  • Cancer
  ?
  • Cancer Metabolism
  ?
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Cancer
  ?
  • Cancer Metabolism
  ?
  • Cellular metabolic process

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  ?
  • Lipid metabolism

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  ?
  • Lipoprotein metabolism

  • Metabolism
  ?
  • Types of disease
  ?
  • Heart disease

應用

靶標

• 相關性APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties
• 細胞定位Secreted

• Anti-APOA4 antibody 圖像

  • 

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4 antibody (ab197844)

    Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling APOA4 with ab197844 at 1/30 dilution.

  • 

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4 antibody (ab197844)