PAK3 polyclonal antibody (A01)
產(chǎn)品名稱： PAK3 polyclonal antibody (A01)
英文名稱： PAK3 polyclonal antibody (A01)
產(chǎn)品編號： H00005063-A01
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant PAK3.
- Immunogen:
- PAK3 (NP_002569, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag.
- Sequence:
- MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGE
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.9 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 5063
- GeneBank Accession#:
- NM_002578
- Protein Accession#:
- NP_002569
- Gene Name:
- PAK3
- Gene Alias:
- CDKN1A,MRX30,MRX47,OPHN3,PAK3beta,bPAK,hPAK3
- Gene Description:
- p21 protein (Cdc42/Rac)-activated kinase 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023855,OTTHUMP00000062894,beta-PAK,oligophrenin-3,p21 (CDKN1A)-activated kinase 3,p21-activated kinase 3,p21-activated kinase-3,serine/threonine-protein kinase PAK 3