Active人MRP8全長蛋白質-蛋白質/抗原/多肽-試劑-生物在線
深圳市宇德立生物科技有限公司
Active人MRP8全長蛋白質

Active人MRP8全長蛋白質

商家詢價

產品名稱： Active人MRP8全長蛋白質

英文名稱： 60B8Ag AI323541 B8Ag BEE11 CAGA Calgranulin-A Calprotectin L1L subunit Calprotectin, included CFAG CGLA Chemotactic cytokine CP-10 CP-10 Cys

產品編號： ab167749

產品價格： 0

產品產地： 英國

品牌商標： abcam

更新時間： null

使用范圍： null

深圳市宇德立生物科技有限公司
  • 聯系人 :
  • 地址 : 深圳市寶安區西鄉寶民二路賢基大廈4E
  • 郵編 :
  • 所在區域 : 廣東
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  • 郵箱 : 1484332550@qq.com

?

  • 性質Recombinant
  • 來源E. coli
  • 氨基酸序列
    • AccessionP05109
    • 種屬Human
    • 序列MLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKG ADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE
    • 分子量11 kDa
    • 氨基酸1 to 93

技術指標

Our?Abpromise guarantee?covers the use of?ab167749?in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Determined by its binding ability with Human CEACAM3 protein in the presence of 100 mM CaCl2.
  • 應用

    SDS-PAGE

    Functional Studies

  • 內毒素水平< 1.000?Eu/μg
  • 純度>95% by SDS-PAGE .
    ab167749 was lyophilized from 0.22 μm filtered solution.
  • 形式Lyophilised
  • 補充說明Determined by its binding ability with Human CEACAM3 protein in the presence of 100 mM CaCl2.
  • 濃度由溶解方法決定?

制備和貯存

  • 穩定性和存儲

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 94% PBS, 5% Trehalose

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 復溶It is recommended to reconstitute the lyophilized antibody in sterile deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

常規信息

  • 別名
    • 60B8Ag
    • AI323541
    • B8Ag
    see all
  • 功能Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
  • 組織特異性Expressed by macrophages in chronic inflammations. Also expressed in epithelial cells constitutively or induced during dermatoses.
  • 序列相似性Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • 細胞定位Secreted. Cytoplasm. Cytoplasm > cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation.
  • Information by UniProt

Active human MRP8 full length protein 圖像