Anti-JIP2/IB2 mAb: APC [S135-37]
產(chǎn)品名稱： Anti-JIP2/IB2 mAb: APC [S135-37]
英文名稱： JIP2/IB2 Monoclonal Antibody: APC [S135-37]
產(chǎn)品編號： SMC-465D-APC
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 加拿大
品牌商標(biāo)： StressMarq
更新時間： null
使用范圍： WB, ICC, IHC
StressMarq
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The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. It is expressed mainly in the cerebellum, pituitary gland, occipital lobe, and the amygdala of the brain, but also in the pancreas, including insulin-secreting cells.