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Human Growth Factors & Cytokines
Recombinant Human FGF-21





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		Synonyms :
Fibroblast Growth Factor-21, FGFL



		Description :
FGF-21 is a secreted growth factor that is a member of the FGF family.  Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.   Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.



		Catalog #:
100-42



		Source :
E.coli



		Purity :
Greater than 90% by SDS-PAGE gel and HPLC analyses



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS 



		PubMed Link :
Human+AND+FGF-21


Country of Origin :
USA
















        Size A
5μg
$80?
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        Size B
25μg
$195?
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        Size C
1mg
$3000?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.