PeproTech重組小鼠BMP-4 10ug
產(chǎn)品名稱: PeproTech重組小鼠BMP-4 10ug
英文名稱: Recombinant Murine BMP-4
產(chǎn)品編號: 315-27
產(chǎn)品價格: 0
產(chǎn)品產(chǎn)地: 美國
品牌商標(biāo): PeproTech
更新時間: null
使用范圍: null
美國PeproTech(派普泰克)公司中國代表處
- 聯(lián)系人 :
- 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區(qū)域 : 江蘇
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- 郵箱 : peprotech.infochina@thermofisher.com
Recombinant Murine BMP-4
Catalog Number:315-27Synonyms:BMP-2, BDVR4Description:Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli derived murine BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.AA Sequence:KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCRKKNK NCRRHSLYVD FSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYL DEYDKVVLKN YQEMVVEGCG CRSource:E.coliPurity:Greater than 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-15 ng/ml.????Research Interests:
Angiogenesis/ Cardiovascular Apoptosis Bone, Skeletal, Cartilage Proliferation Stem Cells & Differentiation TGF-β Superfamily ??Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.
