DYNLL1 (Human) Recombinant Protein (P01)
產品名稱： DYNLL1 (Human) Recombinant Protein (P01)
英文名稱： DYNLL1 (Human) Recombinant Protein (P01)
產品編號： H00008655-P01
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human DYNLL1 full-length ORF ( NP_003737.1, 1 a.a. - 89 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG
- Theoretical MW (kDa):
- 36.8
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8655
- GeneBank Accession#:
- NM_003746.2
- Protein Accession#:
- NP_003737.1
- Gene Name:
- DYNLL1
- Gene Alias:
- DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,MGC126137,MGC126138,PIN,hdlc1
- Gene Description:
- dynein, light chain, LC8-type 1
- Omim ID:
- 601562
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
- Other Designations:
- 8 kDa dynein light chain,cytoplasmic dynein light polypeptide,dynein light chain 1,dynein, cytoplasmic, light polypeptide 1,protein inhibitor of neuronal nitric oxide synthase
- Related Disease