α-1抗胰糜蛋白酶/SERPINA3抗體
產(chǎn)品名稱： α-1抗胰糜蛋白酶/SERPINA3抗體
英文名稱： Alpha-1-Antichymotrypsin
產(chǎn)品編號： bs-0094R
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標(biāo)： 博奧森
更新時間： 2026-04-10T08:58:12
使用范圍： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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Alpha 1-Antichymotrypsin, a member of the serine proteinase inhibitor (serpin) family, inhibits neutrophil proteinase cathepsin G and mast cell chymases, and protects the lower respiratory tract from damage by proteolytic enzymes. It contains a reactive centre loop, which interacts with cognate proteinases, resulting in loop cleavage and a major conformational change. Recently, alpha 1-antichymotrypsin has been identified as a major constituent of the neurofibrillary plaques associated with Alzheimers disease, and in vitro studies have shown that it enhances the rate of amyloid-fibril formation. These observations and recent genetic evidence suggest that alpha 1-antichymotrypsin is important in the pathogenesis of Alzheimers disease.