Anti-Cystatin C Monoclonal Antibody

英文名稱
Anti-Cystatin C Monoclonal Antibody
別名
ARMD11;HEL-S-2
應用
sELISA Capture
稀釋比例
WB 1:1000.
交叉反應
Human
蛋白分子量
13kDa
Gene ID
1471
保存
Store at -20°C. Avoid freeze / thaw cycles.
儲存液
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法
Affinity purification
亞型
IgG1
免疫原
Recombinant human cystatin c protein.
性狀
液體
Public Immunogen Range
Recombinant human cystatin c protein.
Subcellular Locations
Secreted
Swiss Prot
P01034
克隆號
6F12-C7-D8
克隆類型
Monoclonal Antibody
背景資料
Cystatin C or cystatin 3 (formerly gamma trace,post-gamma-globulin or neuroendocrine basic polypeptide),[2] a protein encoded by the CST3 gene,is mainly used as a biomarker of kidney function.Recently,it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease.It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition),such as Alzheimer's disease.In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids.It is found in virtually all tissues and body fluids.It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes).Cystatin C belongs to the type 2 cystatin gene family.