HSP90 monoclonal antibody, clone 8D3
產品名稱： HSP90 monoclonal antibody, clone 8D3
英文名稱： HSP90 monoclonal antibody, clone 8D3
產品編號： MAB6620
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against HSP90.
- Immunogen:
- Ah receptor (Aryl hydrocarbon receptor).
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rabbit, Rat
- Specificity:
- Immunoprecipitates 90KDa proteins corresponding to the molecular mass of Hsp90. Co-immunoprecipitates Hsp90 complexes, including Hsp70, Hop, Ah receptors, glucocorticoid receptors, heme-regulated eukaryotic initiation factor 2alpha (eIF-2alpha) kinase (HRI).
- Form:
- Liquid
- Isotype:
- IgM
- Storage Buffer:
- In PBS (0.09% sodium azide, 50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.
Arlander SJ, Eapen AK, Vroman BT, McDonald RJ, Toft DO, Karnitz LM.J Biol Chem. 2003 Dec 26;278(52):52572-7. Epub 2003 Oct 21.
- 2.
- Hsp90 inhibitors as novel cancer chemotherapeutic agents.
Neckers L.Trends Mol Med. 2002;8(4 Suppl):S55-61.
- 3.
- Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
Whitesell L, Mimnaugh EG, De Costa B, Myers CE, Neckers LM.Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8324-8.
- Application Image
- Immunoprecipitation