BIRC5 polyclonal antibody
產品名稱： BIRC5 polyclonal antibody
英文名稱： BIRC5 polyclonal antibody
產品編號： PAB9714
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 129-142 of Human BIRC5.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation.
Kobayashi K, Hatano M, Otaki M, Ogasawara T, Tokuhisa T.Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1457-62.
- 2.
- Control of apoptosis and mitotic spindle checkpoint by survivin.
Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC.Nature. 1998 Dec 10;396(6711):580-4.
- 3.
- A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma.
Ambrosini G, Adida C, Altieri DC.Nat Med. 1997 Aug;3(8):917-21.
- Entrez GeneID:
- 332
- Gene Name:
- BIRC5
- Gene Alias:
- API4,EPR-1
- Gene Description:
- baculoviral IAP repeat-containing 5
- Omim ID:
- 603352
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
- Other Designations:
- apoptosis inhibitor 4,baculoviral IAP repeat-containing protein 5,survivin variant 3 alpha
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Carcinoma, Adenosquamous
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cell Transformation, Neoplastic
- Colorectal Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Lymphatic Metastasis
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Neovascularization, Pathologic
- Pancreatic Neoplasms