Anti-CHM Polyclonal Antibody-抗體-抗體-生物在線
北京索萊寶科技有限公司--實驗室產品
Anti-CHM Polyclonal Antibody

Anti-CHM Polyclonal Antibody

商家詢價

產品名稱: Anti-CHM Polyclonal Antibody

英文名稱: TCD;GGTA;REP-1;DXS540;HSD-32

產品編號: K008000P

產品價格: null

產品產地: 北京

品牌商標: Solarbio

更新時間: null

使用范圍: IHC

北京索萊寶科技有限公司--實驗室產品
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This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.