Anti-SUMO-1 Rabbit polyclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-SUMO-1 Rabbit polyclonal Antibody

Anti-SUMO-1 Rabbit polyclonal Antibody

商家詢價

產品名稱： Anti-SUMO-1 Rabbit polyclonal Antibody

英文名稱： Anti-SUMO-1 Rabbit polyclonal Antibody

產品編號： 21236

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： ELISA, WB, IHC, IP

武漢紐斯特生物技術有限公司
  • 聯系人 :
  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
  • 電話 : 186****7297 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : neweast3@126.com

?

SUMO-1 [21236]
[100 μL]		 ?

Catalog Number:??21236
Gene Symbol:??SUMO1
Description: ??Anti-SUMO-1 Rabbit polyclonal Antibody
Background: ??Small Ubiquitin-like Modifier or SUMO proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle. There are 3 confirmed SUMO isoforms in humans: SUMO-1, SUMO-2 and SUMO-3. SUMO-2 and -3 show a high degree of similarity to each other and are distinct from SUMO-1.
Immunogen: ??A synthetic peptide corresponding to residues near the C-terminal of human SUMO-1.
Applications: ??ELISA, WB, IHC, IP
Recommended Dilutions: ??
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:100
Concentration: ??1 mg/ml
Host: ??Rabbit
Format: ??Liquid
Clonality: ??Polyclonal
Isotype: ??
Purity: ??Purified from serum
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Detects SUMO-1 but not SUMO-2/3 from vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
?
Western blot:??
Western blot analysis of over-expressed SUMO-1 proteins. HEK293 cells were transfected with SUMO-1 (lane 2) and SUMO-2 (lane 3) cDNAs and control empty vector (lane 1). Cell lysates were blotted with anti-SUMO-1 rabbit polyclonal antibody (Cat. # 21236).

?

Publications:
1.??The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity
????Journal of Cellular Biochemistry Volume 114, Issue 10, pages 2323–2333, October 2013
2.??C-terminal Src Kinase (Csk)-mediated Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) Promotes Proteolytic Cleavage and Nuclear Translocation of eEF2
????J Biol Chem. 2014 May 2;289(18):12666-78