GCLC Rabbit pAb (APR18004N)
產(chǎn)品名稱： GCLC Rabbit pAb (APR18004N)
英文名稱： GCLC Rabbit pAb (APR18004N)
產(chǎn)品編號(hào)： APR18004N
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： Leading Biology
更新時(shí)間： null
使用范圍： WB (Mus musculus, Gallus gallus, Struthio camelus, Rattus norvegicus)
生物谷
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- 地址 : 上海市徐匯區(qū)光啟城辦公樓3樓
- 郵編 : 100176
- 所在區(qū)域 : 上海
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分子量：Calculated MW: 72kDa Observed MW: 72kDa 稀釋方法：WB 1:500 - 1:3000 IF 1:50 - 1:200 總結(jié)：Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.