OCT4 Rabbit pAb (APR27816N)-抗體-抗體-生物在線
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OCT4 Rabbit pAb (APR27816N)

OCT4 Rabbit pAb (APR27816N)

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產品名稱: OCT4 Rabbit pAb (APR27816N)

英文名稱: OCT4 Rabbit pAb (APR27816N)

產品編號: APR27816N

產品價格: null

產品產地: 美國

品牌商標: Leading Biology

更新時間: null

使用范圍: IHC (HeLa cells, Homo sapiens, Mus musculus) IF (HeLa cells) WB (Homo sapiens, Mus musculus)

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分子量:Calculated MW: 30kDa/38kDa
Observed MW: 45KDa

細胞定位:Cytoplasm, Nucleus

稀釋方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200

總結:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.