AddexBio LS-180 cells (結(jié)直腸腺癌) LS-180 cells(C0009006)
產(chǎn)品名稱： AddexBio LS-180 cells (結(jié)直腸腺癌) LS-180 cells(C0009006)
英文名稱： LS-180 cells
產(chǎn)品編號(hào)： C0009006
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： AddexBio
更新時(shí)間： null
使用范圍： null
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Disease: Colorectal adenocarcinoma Origin: Derived from a 58 year old female Caucasian with Dukes type B adenocarcinoma of the colon Species: Homo sapiens Tissue: Colon Morphology: Epithelial Properties: Adherent Cytogenic data: Tumorigenic, Modal no. 45 (2n=46) Patient: Female, Caucasian, 58 yrs of age Medium: MEM + 10% FBS Subculture: 1:2 to 1:4 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: HLA A2, B13, B50, IL6, IL10, mucin Isoenzymes: ADA, 1; ES-D, 1; G6PD, B; PEP-D, 1; PGD, A; PGM1, 1; PGM3, 2 DNA Profile (STR): Amelogenin: X ; CSF1PO: 10,13; D13S317: 10; D16S539: 11,13; D5S818: 10,15; D7S820: 11,9.3; THO1: 6,7; TPOX: 8,9; vWA: 15,18 Mutations in LS-180 Cells Related cells by Organ: Caco-2 cells DLD-1 cells HCA-7 cells HCT-116 cells SW480 cells HT-29 cells LS-180 cells SW620 cells T84 cells SW48 cells RKO cells SNU-407 cells SNU-503 cells LS-174T cells LoVo cells HCT15 cells References for LS-180 cells: 1. Bass, S. E., Sienkiewicz, P., Macdonald, C. J., Cheng, R. Y., Sparatore, A., Del Soldato, P., Roberts, D. D., Moody, T. W., Wink, D. A., and Yeh, G. C. Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells. Clin Cancer Res, 15: 1964-1972, 2009. 2. Fukumori, S., Masago, M., Ishida, K., Kayano, Y., Taguchi, M., and Hashimoto, Y. Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells. Biopharm Drug Dispos, 30: 448-456, 2009. 3. Graber-Maier, A., Buter, K. B., Aeschlimann, J., Bittel, C., Kreuter, M., Drewe, J., and Gutmann, H. Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180. Planta Med, 76: 1866-1870. 4. Ishida, K., Takaai, M., Yotsutani, A., Taguchi, M., and Hashimoto, Y. Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells. Biol Pharm Bull, 32: 741-745, 2009. 5. Takaai, M., Morishita, H., Ishida, K., Taguchi, M., and Hashimoto, Y. Contribution of Na+-independent nucleoside transport to ribavirin uptake in the rat intestine and human epithelial LS180 cells. Eur J Pharmacol, 601: 61-65, 2008. 6. Yamasaki, D., Nakamura, T., Okamura, N., Kokudai, M., Inui, N., Takeuchi, K., Watanabe, H., Hirai, M., Okumura, K., and Sakaeda, T. Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells. Eur J Pharm Sci, 37: 126-132, 2009.