Anti-RGR Polyclonal Antibody
產品名稱: Anti-RGR Polyclonal Antibody
英文名稱: RP44
產品編號: K007139P
產品價格: null
產品產地: 北京
品牌商標: Solarbio
更新時間: null
使用范圍: WB IHC
北京索萊寶科技有限公司--實驗室產品
- 聯系人 :
- 地址 : 北京市通州區馬駒橋聯東U谷景盛南四街85A三層
- 郵編 :
- 所在區域 : 北京
- 電話 : 010-563*1250 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 2748554845@qq.com
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
