GPC3 polyclonal antibody
產品名稱： GPC3 polyclonal antibody
英文名稱： GPC3 polyclonal antibody
產品編號： PAB9896
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Sheep polyclonal antibody raised against partial recombinant GPC3.
- Immunogen:
- Recombinant protein corresponding to C-terminus of human GPC3.
- Host:
- Sheep
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (5-10 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Value of glypican 3 immunostaining in the diagnosis of hepatocellular carcinoma on needle biopsy.
Anatelli F, Chuang ST, Yang XJ, Wang HL.Am J Clin Pathol. 2008 Aug;130(2):219-23.
- 2.
- Expression of glypican 3 in ovarian and extragonadal germ cell tumors.
Zynger DL, Everton MJ, Dimov ND, Chou PM, Yang XJ.Am J Clin Pathol. 2008 Aug;130(2):224-30.
- 3.
- Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR.Hepatology. 2008 Apr;47(4):1211-22.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 2719
- Gene Name:
- GPC3
- Gene Alias:
- DGSX,OCI-5,SDYS,SGB,SGBS,SGBS1
- Gene Description:
- glypican 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000024058,OTTHUMP00000062492,glypican proteoglycan 3