Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
產品名稱： Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
英文名稱： Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
產品編號： 94051ES
產品價格： 詢價
產品產地： Yeasen
品牌商標： Yeasen
更新時間： 2026-02-10T16:59:54
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
產品介紹
GPNMB (Glycoprotein Nonmetastatic B) is a transmembrane glycoprotein encoded by the human gene GPNMB, belonging to the immunoglobulin superfamily. Below is a detailed introduction to the GPNMB protein.
GPNMB is involved in interactions between cells, promoting cell adhesion and migration, which is particularly important in embryonic development and tissue repair. As a cell surface antigen, GPNMB plays a crucial role in regulating immune responses. It can influence macrophage polarization and modulate inflammatory responses. GPNMB has been found to be highly expressed in various cancers, such as melanoma, breast cancer, and lung cancer. Research indicates that it may contribute to tumor progression by promoting the survival, proliferation, and metastasis of tumor cells.
Research on the GPNMB protein is ongoing, with the scientific community exploring its roles in various biological processes and its potential as a therapeutic target for diseases. Moreover, advancements in technology (such as single-cell RNA sequencing and high-throughput screening) provide new opportunities for a deeper understanding of GPNMB's functions and regulation.
產品性質
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產品別稱
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GPNMB,HGFIN,NMB,Osteoactivin
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種屬
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Human
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表達序列
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Ala 22 - Pro 486
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Accession
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AAH32783
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標簽
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C-His-Avi Tag
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表達系統
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HEK293
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分子量
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The protein has a predicted MW of 53.7 kDa
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純度
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> 95% as determined by SDS-PAGE
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內毒素
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< 1.0 EU per μg by the LAL method.
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制劑
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外觀
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Liquid
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生物活性
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ELISA:Biotinylated Human GPNMB Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-GPNMB hlgG2 Antibody were added.
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產品特色
高純度、高活性、低內毒素、高批間一致性
應用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Biotinylated Human GPNMB Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-GPNMB hlgG2 Antibody were added.
存儲條件
-85 ~ -65℃保存，收到貨之日起，6個月有效期。避免反復凍融，建議等分分裝為一次實驗使用量，分裝后，-80℃凍存。