KANK1 Rabbit pAb (APR23528N)
產品名稱: KANK1 Rabbit pAb (APR23528N)
英文名稱: KANK1 Rabbit pAb (APR23528N)
產品編號: APR23528N
產品價格: null
產品產地: 美國
品牌商標: Leading Biology
更新時間: null
使用范圍:
分子量:Calculated MW: 129kDa/147kDa Observed MW: Refer to figures 稀釋方法:WB 1:500 - 1:2000 IF 1:50 - 1:200 總結:The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.
