BCL2A1 (Human) Recombinant Protein (Q01)
產品名稱： BCL2A1 (Human) Recombinant Protein (Q01)
英文名稱： BCL2A1 (Human) Recombinant Protein (Q01)
產品編號： H00000597-Q01
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human BCL2A1 partial ORF ( AAH16281, 31 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNT
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 597
- GeneBank Accession#:
- BC016281
- Protein Accession#:
- AAH16281
- Gene Name:
- BCL2A1
- Gene Alias:
- ACC-1,ACC-2,BCL2L5,BFL1,GRS,HBPA1
- Gene Description:
- BCL2-related protein A1
- Omim ID:
- 601056
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- hematopoietic BCL2-related protein A1
- Gene Pathway
- Related Disease
- Cardiovascular Diseases
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoproliferative Disorders
- Occupational Diseases
- Waldenstrom Macroglobulinemia
- Werner syndrome