BACE1 monoclonal antibody (M02), clone 2C13
產品名稱： BACE1 monoclonal antibody (M02), clone 2C13
英文名稱： BACE1 monoclonal antibody (M02), clone 2C13
產品編號： H00023621-M02
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full-length recombinant BACE1.
- Immunogen:
- BACE1 (AAH65492, 22 a.a. ~ 501 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
- Host:
- Mouse
- Reactivity:
- Human, Rat
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (78.54 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- BACE1 monoclonal antibody (M02), clone 2C13. Western Blot analysis of BACE1 expression in rat testis.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged BACE1 is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 23621
- GeneBank Accession#:
- BC065492
- Protein Accession#:
- AAH65492
- Gene Name:
- BACE1
- Gene Alias:
- ASP2,BACE,FLJ90568,HSPC104,KIAA1149
- Gene Description:
- beta-site APP-cleaving enzyme 1
- Omim ID:
- 604252
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- APP beta-secretase,aspartyl protease 2,beta-secretase,beta-site amyloid beta A4 precursor protein-cleaving enzyme,beta-site amyloid precursor protein cleaving enzyme,memapsin-2,membrane-associated aspartic protease 2,transmembrane aspartic proteinase Asp2
- Interactome
- Gene Pathway