SNCA monoclonal antibody (M01), clone 2E4
產品名稱： SNCA monoclonal antibody (M01), clone 2E4
英文名稱： SNCA monoclonal antibody (M01), clone 2E4
產品編號： H00006622-M01
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SNCA.
- Immunogen:
- SNCA (NP_000336, 31 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- GKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of SNCA expression in transfected 293T cell line by SNCA monoclonal antibody (M01), clone 2E4.
Lane 1: SNCA transfected lysate(14.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of SNCA transfected lysate using anti-SNCA monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SNCA MaxPab rabbit polyclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged SNCA is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 6622
- GeneBank Accession#:
- NM_000345
- Protein Accession#:
- NP_000336
- Gene Name:
- SNCA
- Gene Alias:
- MGC110988,NACP,PARK1,PARK4,PD1
- Gene Description:
- synuclein, alpha (non A4 component of amyloid precursor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
- Interactome
- Gene Pathway
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Association Learning
- Attention
- Cardiovascular Diseases
- Chromosome Breakage
- Cognition Disorders
- Color Perception
- Cystic Fibrosis
- Cystic fibrosis
- Dementia
- Diabetes Complications
- Disease Progression
- Disease Susceptibility
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease