ERBB3 monoclonal antibody, clone 2F9
產(chǎn)品名稱(chēng)： ERBB3 monoclonal antibody, clone 2F9
英文名稱(chēng)： ERBB3 monoclonal antibody, clone 2F9
產(chǎn)品編號(hào)： MAB10585
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant ERBB3.
- Immunogen:
- Recombinant hIgGFc tag fusion protein corresponding to extracellular fragment at amino acids 22-369 of human ERBB3.
- Host:
- Mouse
- Theoretical MW (kDa):
- 148
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis using ERBB3 monoclonal antibody, clone 2F9 (Cat # MAB10585) against human ERBB3 (aa 22-369) -hIgGFc trasfected HEK293 cell lysate.
- Entrez GeneID:
- 2065
- Gene Name:
- ERBB3
- Gene Alias:
- ErbB-3,HER3,LCCS2,MDA-BF-1,MGC88033,c-erbB-3,c-erbB3,erbB3-S,p180-ErbB3,p45-sErbB3,p85-sErbB3
- Gene Description:
- v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq
- Other Designations:
- erbB-3,lethal congenital contracture syndrome 2,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
- Interactome
- Related Disease
- Addison Disease
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Bipolar Disorder
- Brain Neoplasms
- Carcinoma
- Cardiovascular Diseases
- Celiac Disease
- Coronary Artery Disease
- Crohn Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Glioma
- Hypertension
- Multiple Sclerosis
- Ovarian Neoplasms
- Prostatic Neoplasms