PP6C Antibody
產(chǎn)品名稱： PP6C Antibody
英文名稱： PP6C Antibody
產(chǎn)品編號(hào)： 252096
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： Abbiotec
更新時(shí)間： null
使用范圍： E: 1:10,000-1:50,000; WB: 1:500-1:2,000
深圳市豪地華拓生物科技有限公司
- 聯(lián)系人 :
- 地址 : 深圳市南山創(chuàng)業(yè)路中興城5棟518
- 郵編 : 518054
- 所在區(qū)域 : 廣東
- 電話 : 132****4656 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : order@otwobiotech.com
Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C A) is the catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PP6C A restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PP6C A downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. PP6C A is ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.