Product name:Ipilimumab (?伊匹木單抗?)

Catalog No. :?FrdE00033

MW:148000.00 Da

Description:Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells.3 CTLA-4 and CD28 are both presented on the surface of T-cells.3 Ipilimumab is a human IgG1 that binds CTLA-4, preventing the inhibition of T-cell mediated immune responses to tumors.

Alternative names:Ipilimumab

Specificity target name;species:CTLA4/CD152[Homo sapiens]

Form:?Liquid

Receptor identification:IgG1-kappa

Storage:?Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.

Purity:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Note:?This product is for research use only,not for diagnostic or therapeutic use.